The results of a 1980 clinical trial on heart drug Lorcainide were not published until a decade later. Doctors didn’t know that more people died in the trial who were given Lorcainide than who were taking the placebo. It has been estimated that over 100,000 people died avoidably because they were prescribed drugs in the same class. Read about how the researchers were able to get the results of the study published.
Dr Ben Goldacre prescribed the antidepressant Reboxetine for a patient but says he was “misled.” Results from trials which showed it was worse than other drugs were withheld, while the smaller number of trials which showed it worked better were published.
The UK Government has spent £424 million stockpiling Tamiflu, an anti-flu treatment, but we still don’t know if this treatment works any better than placebo. Regulators weren’t given information from all the clinical trials done on Tamiflu. The manufacturers of Tamiflu didn’t break any laws by withholding the information.